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Lisa Wang Selected Research

2,2- dimethyl- N- (6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- N'- (2,2,3,3,3- pentafluoropropyl)malonamide

5/2015A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia.
4/2014A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575).
10/2013A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors.

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Lisa Wang Research Topics

Disease

44Neoplasms (Cancer)
06/2022 - 01/2006
7Colorectal Neoplasms (Colorectal Cancer)
12/2021 - 05/2005
7Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 03/2006
7Prostatic Neoplasms (Prostate Cancer)
01/2021 - 12/2010
7Fatigue
09/2020 - 10/2011
6Hypertension (High Blood Pressure)
05/2022 - 01/2010
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 11/2008
6Ovarian Epithelial Carcinoma
01/2021 - 06/2010
5Disease Progression
01/2022 - 04/2008
5Neoplasm Metastasis (Metastasis)
01/2021 - 06/2013
4Hepatocellular Carcinoma (Hepatoma)
06/2022 - 04/2004
4Diarrhea
01/2022 - 10/2016
4Breast Neoplasms (Breast Cancer)
09/2020 - 01/2010
4Squamous Cell Carcinoma of Head and Neck
10/2016 - 02/2011
3Endometrial Neoplasms (Endometrial Cancer)
01/2022 - 08/2014
3Neutropenia
01/2021 - 01/2010
3Renal Cell Carcinoma (Grawitz Tumor)
01/2019 - 04/2008
3Carcinoma (Carcinomatosis)
12/2018 - 06/2012
3Adenocarcinoma
12/2018 - 06/2012
3Hemorrhage
01/2017 - 01/2007
3Ascites
07/2010 - 03/2006
2Carcinosarcoma
01/2022 - 08/2014
2Pain (Aches)
11/2020 - 10/2014
2Melanoma (Melanoma, Malignant)
05/2019 - 04/2016
2Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2019 - 12/2018
2Infections
10/2017 - 02/2011
2Hypoxia (Hypoxemia)
01/2017 - 06/2012
2Pancreatic Neoplasms (Pancreatic Cancer)
01/2016 - 06/2012
2Head and Neck Neoplasms (Head and Neck Cancer)
01/2016 - 09/2011
2Anemia
10/2013 - 06/2012
2Mucositis
10/2013 - 07/2012
2Lymphoma (Lymphomas)
03/2011 - 05/2009
2Brain Neoplasms (Brain Tumor)
11/2009 - 04/2007
2Peritoneal Neoplasms
03/2006 - 05/2005
1Salivary Gland Neoplasms (Salivary Gland Cancer)
01/2022
1Thrombocytopenia (Thrombopenia)
01/2021
1Chromosome Aberrations (Chromosome Abnormalities)
11/2020
1Brachial Plexus Neuritis (Parsonage Turner Syndrome)
11/2020
1Bursitis (Adhesive Capsulitis)
11/2020

Drug/Important Bio-Agent (IBA)

8PlatinumIBA
01/2021 - 11/2009
6Sorafenib (BAY 43-9006)FDA Link
01/2017 - 04/2008
5GemcitabineFDA Link
01/2021 - 07/2010
5Pharmaceutical PreparationsIBA
01/2020 - 05/2005
5Proteins (Proteins, Gene)FDA Link
02/2019 - 01/2006
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2019 - 03/2006
4ErbB Receptors (EGF Receptor)IBA
01/2022 - 03/2010
4Bevacizumab (Avastin)FDA Link
01/2021 - 11/2009
4DNA (Deoxyribonucleic Acid)IBA
01/2020 - 10/2016
4Docetaxel (Taxotere)FDA Link
01/2019 - 04/2011
4Sunitinib (Sutent)FDA Link
01/2019 - 08/2014
4Drug CombinationsIBA
10/2013 - 04/2007
4Messenger RNA (mRNA)IBA
01/2013 - 01/2006
4Albendazole (Albenza)FDA Link
07/2010 - 05/2005
3cabozantinibIBA
06/2022 - 01/2020
3Biomarkers (Surrogate Marker)IBA
06/2022 - 04/2014
3Immune Checkpoint InhibitorsIBA
01/2022 - 01/2019
3Paclitaxel (Taxol)FDA LinkGeneric
11/2020 - 09/2010
3Cisplatin (Platino)FDA LinkGeneric
10/2016 - 04/2011
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
04/2016 - 01/2010
3cediranib (AZD2171)IBA
04/2016 - 08/2013
3Amyloid Precursor Protein Secretases (beta-Secretase)IBA
05/2015 - 10/2013
32,2- dimethyl- N- (6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- N'- (2,2,3,3,3- pentafluoropropyl)malonamideIBA
05/2015 - 10/2013
3VorinostatFDA Link
01/2015 - 05/2009
3DecitabineFDA Link
01/2015 - 05/2009
3Erlotinib Hydrochloride (CP 358,774)FDA Link
06/2012 - 11/2009
2trametinibIBA
02/2022 - 12/2021
2Alanine Transaminase (SGPT)IBA
01/2022 - 04/2015
2Tyrosine Kinase InhibitorsIBA
01/2022 - 12/2010
2EnzymesIBA
01/2022 - 01/2007
2VaccinesIBA
11/2020 - 03/2011
2Cytokine Receptors (Cytokine Receptor)IBA
01/2020 - 10/2007
2Pantoprazole (Protonix)FDA LinkGeneric
01/2019 - 12/2014
2dacomitinibIBA
10/2017 - 10/2016
2pazopanibFDA Link
04/2015 - 01/2010
2Capecitabine (Xeloda)FDA Link
08/2014 - 05/2012
2src-Family KinasesIBA
01/2014 - 06/2012
2saracatinibIBA
01/2014 - 06/2012
2Antineoplastic Agents (Antineoplastics)IBA
01/2011 - 04/2007
1SmokeIBA
05/2022
1Angiogenesis InhibitorsIBA
01/2022
1AfatinibIBA
01/2022
1NivolumabIBA
01/2022
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2022
1Panitumumab (Vectibix)FDA Link
12/2021
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2021
1Cell-Free Nucleic AcidsIBA
12/2021
1adavosertibIBA
01/2021
1Radium-223IBA
01/2021
1Circulating Tumor DNAIBA
01/2021
1SteroidsIBA
11/2020
1Gabapentin (Neurontin)FDA LinkGeneric
11/2020

Therapy/Procedure

20Drug Therapy (Chemotherapy)
01/2022 - 11/2009
18Therapeutics
01/2022 - 01/2007
11Radiotherapy
01/2020 - 04/2011
6Castration
01/2021 - 04/2011
5Immunotherapy
01/2022 - 12/2018
2Adjuvant Radiotherapy
09/2020 - 01/2016
1Liver Transplantation
06/2022
1Precision Medicine
01/2022
1Intramuscular Injections
11/2020